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Human DNA is about 99.5% identical from person to person. It is the instruction manual of all our body, instructing our cells how to function! However, there are small differences in our DNA that make each person unique. These differences are called variants. Variants can be linked to certain health conditions, traits and ancestry groups.
A person's microbiome is the entire collection of microbes living in and on the body (mouth, nose, gut, etc..).
When the microbes in your gut are out of balance, your body can't absorb nutrients the way it should. The result of this is inflammation, the root of almost every chronic disease.
Dnomium uses a very new technology called 'low-coverage sequencing' to analyse these variants. Compared to our competitors, we can collect x50 more data from your DNA. It analyses all mutations that may impact your health, providing you with more accurate and comprehensive results.
Only 1% of your body's gene expression is done by your DNA! The rest is done by your unique microbiome! That's why Dnomium captures everything that is happening, not only in your DNA, but also in your unique microbiome. By analysing your living microorganisms, in addition to your DNA data, our AI technology takes the guesswork out of eating right!
Our algorithm breaks down your DNA in order to give you a report about your global ancestry by percentages.
Learn if you are at an increased risk of developing +200 health conditions (including cancers) and how to maximize your brain wellness. If you are starting a family, also learn if both parents are carrier of genetic variants that could be harmful to their children's health. Even if most of these reports contain prevention strategies, you should always consult your doctor before taking any action because our service is for educational purposes only!
The diet & training that works for everyone else is not necessarily what best fits you. We interpret your microbiome & DNA data to find out how your inside chemistry deals with training & diet. We also create specific advices & plans according to different goals: fat loss, muscle building, endurance & strength performance.
The future of your skin's health is written in your DNA and your microbiome. Various proteins produced by our DNA act on every aspect of it such as collagen degradation, collagen synthesis, glycation, etc...
Learn the proper preventive strategies to upgrade your skin's future.
Response to various drugs and especially their side effects are highly managed by our DNA. The study of these is called pharmacogenetics.
We use this science to interpret your DNA data and create your reports, so you and your medical practitioner can make smarter decisions when it comes to your medication regimen.
Did you know that approximately 600 species of microbes are living comfortably in your mouth and 40 trillion different organisms in your gut?
Some of them are beneficial for your health, and others are harmful.
The ratios of different harmful bacteria in your mouth and your gut can influence your level of protection for different diseases such as obesity, gum diseases, cavities, type II diabetes, Crohn's disease, etc...
Our artificial intelligence technology not only analyses your DNA, but also your mouth & gut microbiome in order to give you a better insight about your little neighbors.
Highly recommended for health
We collect 50 times MORE measurements per genome than genotyping technologies used by our competitors
Over the last ten years, the field of human genomics has made unbelievable progress in identifying genetic variants that influence disease susceptibility and other traits. The technological advance that drove this progress was the development of genotyping microarrays: a technology for the measurement of hundreds of thousands to millions of genetic variants in a single person. These genotyping microarrays are also used by all DNA testing companies such as 23andMe, AncestryDNA, MyHeritage.
In this post, we argue that genotyping arrays are now less effective and more expensive than sequencing technologies.
Today, slightly more than a million people have had their whole genomes sequenced. Compare that to the 17 million estimated to have had their DNA analyzed with direct-to-consumer tests sold by 23andMe and Ancestry. They use a technology called genotyping, which takes about a million snapshots of a person's genome. That might sound like a lot, but it's really less than 1 percent of the full picture. On the other side, sequencing technology analyses 100% percent of the full picture! Genotyping targets short strings of DNA that scientists already know have a strong association with a given trait. So say, for example, scientists discover a new gene that increases your risk of developing brain cancer. If that gene is not one that 23andMe looks at (because how would it know to look if the gene hasn't been discovered yet), then you'd have to get tested all over again to learn more about your brain cancer risk. Whole genome data on the other hand, once you have it, can be queried with computer algorithms whenever a new genetic discovery gets made.
Simply because the prices of a full DNA sequencing are too high. But at Dnomium, we developed a low-coverage genome sequencing assay that outperforms genotyping microarrays, at the same price!! Compared with deep sequencing strategies, low-coverage whole-genome sequencing produces a mere fraction of the data per sample and relies on computational methods to fill in the missing information. We developed imputation algorithms for sequencing data to call variants across the whole genome with high accuracy (average imputation r2 over 0.9). Additionally, our standard data analysis includes oral microbiome profiling of every sample.
quinidine (Various brands)
hydrocortisone tacrolimus (Prograf)
doxepin (Sinequan, Silenor, Prudoxin, Zonalon)
phenobarbital triazolam (Halcion)
fentanyl (Actiq, Duragesic, Sublimaze)
ibuprofen (Advil, Motrin)
lidocaine (xylocaine, various brands)
atorvastatin (Lipitor, Caduet)
metoprolol (Lopressor, Toprol)
nifedipine (Adalat, Procardia)
clopidogrel ++ (Plavix)
ifosfamide tamoxifen ++ (Nolvadex)
vincristine (Vincasar, Oncovin)